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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

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Sulfasalazine & Ulcerative Colitis (UC)

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Sulfasalazine is a well-established medication that has been approved for the treatment of ulcerative colitis (UC) by both the FDA and EMA for many years. It continues to be a cornerstone therapy in managing UC, particularly for patients with mild to moderate forms of the disease. This drug is acknowledged as one of the earliest effective treatments developed for this condition (1, 2, 3)

References:

(1) Sebastian et al. 2024 Spartan Med Res J 9(3): 123397
(2) Hayllar & Bjarnason 1991 Gut 32(5): 462-3
(3) Freeman 2012 Clin Med Insights Gastroenterol 5: 77-83

References (Sources)

An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis
LENNARD-JONES et al. 1960 Gut 1(3): 217-22
Current Pharmacologic Options and Emerging Therapeutic Approaches for the Management of Ulcerative Colitis: A Narrative Review
Sebastian et al. 2024 Spartan Med Res J 9(3): 123397
Review
Medical management of ulcerative colitis with a specific focus on 5-aminosalicylates
Freeman 2012 Clin Med Insights Gastroenterol 5: 77-83
Review
Sulphasalazine in ulcerative colitis: in memoriam?
Hayllar & Bjarnason 1991 Gut 32(5): 462-3
Review

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12/17/2025

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