meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Probiotics (living agents) & Ulcerative Colitis (UC)
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Contents
Probiotics are a potential treatment modality for ulcerative colitis (UC), but their efficacy is often compromised by gastrointestinal disease
Low-certainty evidence suggests that probiotics may induce clinical remission in active Ulcerative Colitis (UC) when compared to placebo. There may be little or no difference in clinical remission with probiotics alone compared to 5-ASA. There is limited evidence from a single study which failed to provide a definitio…
References (Sources)
- Clinical trial: Probiotic treatment of acute distal ulcerative colitis with rectally administered Escherichia coli Nissle 1917 (EcN)
- Double-blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitis
- Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis
- Gastrointestinal Microbiome – What We Need to Know in Clinical PracticeReview
- Probiotics for induction of remission in ulcerative colitis
- Randomized placebo-controlled trial assessing the effect of bifidobacteria-fermented milk on active ulcerative colitis
- Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease