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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Interleukin-6 (IL-6) & T helper 17 cell (Th17)

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Interleukin-6 (IL-6) signaling leads to the activation of STAT3 and subsequent induction of RORγt, one of the key transcription factors of T helper 17 cell (Th17), and of other Th17 cell-related factors such as IL-17A/F and Interleukin-23 Receptor (IL23R)
Bettelli et al. 2006 Nature 441(7090): 235-8
Ivanov et al. 2006 Cell 126: 1121-33
Mangan et al. 2006 Nature 441(7090)…

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
Bettelli et al. 2006 Nature 441(7090): 235-8
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
Veldhoen et al. 2006 Immunity 24(2): 179-89
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivanov et al. 2006 Cell 126: 1121-33
Transforming growth factor-beta induces development of the T(H)17 lineage
Mangan et al. 2006 Nature 441(7090): 231-4

5/29/2026