meRfi®-GM
Takeda G-Protein-Coupled Receptor 5 (TGR5 ; BG37 ; GBPAR1)
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Contents
Takeda G-protein-coupled receptor 5 (TGR5, GPBAR) is a class A G-protein-coupled receptor (GPCR) that is expressed in the liver, skeletal muscle, intestine, and brown adipose tissues
In most cells, Takeda G-protein-coupled Receptor 5 (TGR5, BG37, GBPAR1) couples with G-alfa-s
TGR5 is a G protein-coupled receptor expressed in adipocytes, skeletal muscle, intestine and macrophage…
References (Sources)
- Bile Acid-Activated Receptors: A Review on FXR and Other Nuclear Receptors
- Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice
- Discovery, optimization, and evaluation of non‐bile acid FXR/TGR5 dual agonists
- Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation
- Expression and function of the bile acid receptor TGR5 in Kupffer cells
- Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
- The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis