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Sulfonate-respiring bacteria play a central role in the complete anaerobic decomposition of sulfoquinovose (SQ) in the gut. In the human gut, the breakdown of SQ by primary bacteria (e.g., Agathobacter rectalis) produces 2,3-dihydroxy-1-propanesulfonate (DHPS), which then serves as a substrate for secondary sulfonate-respiring bacteria like Bilophila wadsworthia and Desulfovibrio spp. They convert DHPS into Hydrogen Sulfide (H2S) via specialized metabolic pathways (e.g., dissimilatory sul…