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Mother-to-infant transmission of the microbiome is important for the acquisition of a healthy infant microbiota in the early phase of life (from birth to age 3 years).
Bacteroides fragilis uses a range of binding proteins to capture extracellular Human Milk Oligosaccharides (HMOs) and perform their metabolism intracellularly, while using the sialidase NanH (BF1806) and other enzymes in HMO PUL 1 as a central enzymatic system for depolymerization of HMO…