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The cyclic movement of bile salts in the hepatobiliary tree, intestinal tract, and portal venous system is termed the enterohepatic circulation
Bile salt receptors in the enterohepatic system: Nuclear Bile Salt Receptors (alternative nuclear receptors, namely the constitutive androstane receptor (CAR), pregnane-x receptor (PXR), and vitamin D3 receptor (VDR)), Plasma Membrane Receptors for Bile Salts (bile salts transactivate the EGFR by influencing membrane shedding of canonical EGFR ligands, Activation of muscarinic M2 receptors by conjugated CA has been implicated in Arrhythmias)