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Flavonoids are a diverse group of polyphenolic compounds found in various fruits, vegetables, and other plant-based foods. They are known for their numerous health benefits, including antioxidant, anti-inflammatory, and anti-carcinogenic properties. Flavonoids can be classified into several subgroups based on their chemical structure.
Contrary to observations in mice, the success of flavonoids in human dietary cancer prevention trials is often dampened due to large interpersonal variation. Antioxidants activity alone does not explain this variability, suggesting there is an additional important variable that has not been accounted for. Since flavonoids have a poor bioavailability and pred…