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In the context of Colorectal Cancer (CRC) & Fusobacterium nucleatum, Fusobacterium nucleatum (Fn) is consistently linked to an immunosuppressive tumor microenvironment in colorectal cancer (CRC). It adheres to Colorectal Cancer cells via Fap2–Gal‑GalNAc interactions, activates oncogenic signaling, promotes Epithelial-Mesenchymal-Transition (EMT), and supports tumor growth, particularly in Microsatellite stable (MSS) colorectal cancer (CRC) (2), and shapes the tumor immune microenvironment (TIM) by recruiting [M…