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Antimicrobial resistance (AMR / AR)
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Contents
Antimicrobial resistance is a phenomenon where pathogens, such as bacteria, evolve to resist the effects of bactericidal drugs. When a pathogen becomes resistant to multiple categories of drugs, typically three or more clinically significant types, it is referred to as multidrug resistance (MDR). This issue of Antimicrobial resistance (AMR / AR) is increasingly becoming a global health problem, especially in developing countries. For example, bacterial AMR was responsible for 1.27 million and 1.14 million deaths in 2019 and 2021, respective…
References (Sources)
- A bottom-up view of antimicrobial resistance transmission in developing countries
- Antimicrobial resistance in low- and middle-income countries: current status and future directions
- Clinically relevant antibiotic resistance genes are linked to a limited set of taxa within gut microbiome worldwide
- Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050
- Heterologous expression of bacterial natural product biosynthetic pathways
- The gut microbiome: an emerging epicenter of antimicrobial resistance?
- The resistance within: Antibiotic disruption of the gut microbiome and resistome dynamics in infancy