meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Interleukin-17F (IL-17F)
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Contents
IL-17F Producers/Coming from
Th17, CD8 cells, γδTCR+ T cells, NK, NKT, LTi
Gaffen 2009 Nat Rev Immunol 9(8): 556-67
IL-17F Molecular Target/Signaling
IL-17F binds to the IL-17RA-IL-17RC complex with lower affinity than IL-17A and activates the NF-κB and MAPK pathways
Gaffen 2009 Nat Rev Immunol 9(8): 556-67
IL-17F Effects
Neutrophil recruitment, immunity to extracellular pathogens
Gaffen 2009 Nat Rev Immunol 9(8): 556-67
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