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Chimeric antigen receptors (CARs) are synthetic receptor proteins that have been engineered to give T cells the ability to recognize and bind to specific proteins, or antigens, on the surface of cancer cells
Adoptive T Cell Therapy / CAR-T uses T cells that have been genetically modified to express CARs to treat cancer.
Chimeric antigen receptor (CAR) expressing immune cells could be redirected towards Tumor-associated carbohydrates (TACA)-presenting tumors.
Mantuano et al. 2020
Chimeric antigen receptors (CAR) functionally redirect T cells with high specificity to surface antigens on tumor cells independent of MHC restriction and [antigen proc…