meRfi®-GM
Cancer microbiome / Tumor microbiota
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Contents
Microbial metabolites in the tumor microenvironment can significantly influence cancer immunotherapy. It is crucial to distinguish between metabolites from intratumoral microbes and those from the gut microbiota.
There are three primary mechanisms by which microbes transform into intratumoral microbes:
- Translocation through Mucosal Barriers
- Origination from Surrounding Normal Tissues
- Translocation via Blood and Lymphatic Vessels
Microbes residi…
References (Sources)
- Distinct microbial signatures associated with different breast cancer types
- Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain
- Interaction between the microbiome and TP53 in human lung cancer
- Microbiota in tumors: from understanding to application
- Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
- The metabolic dialogue between intratumoural microbes and cancer: implications for immunotherapy
- The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies