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Immunomodulatory factors that affect the bone marrow (BM) microenvironment may play a role in the development of Multiple Myeloma (MM) / Plasmocytoma. The gut microbiota influences the BM microenvironment. Dysbiosis may, therefore, influence tumorigenesis in Multiple Myeloma (MM) / Plasmocytoma. Plasma cell malignancy, a cancer of the adaptive immune system, deserves special attention when it comes to the interface of gut microbiota and the immune system.
The [composition of the microbiome](brain://jEas-yiPy0CuAf…