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Carcinogenesis / Oncogenesis / Tumorigenesis & Cyclomodulins

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Contents

Cyclomodulins can disrupt key processes in eukaryotic cells, potentially leading to pathological changes and contributing to oncogenesis
Zhang et al. 2018i Sci Rep 8: 17780
Markelova et al. 2022 Int J Mol Sci. 23(19): 11706

Cyclomodulins can dysregulate the cell cycle, impact cell differentiation and apoptosis, and play a role in colonic oncogenesis
Buc et al. 2013 PLoS One 8: e56964
Doocey et al. 2022 BMC Microbiol. 22: 53

Some Escherichia coli strains produce toxins designated cyclomodulins (CMs) which interfere with the [eukary…