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Interleukin-10 (IL-10)

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Contents

Interleukin-10 (IL-10) is a crucial anti-inflammatory cytokine that limits immune cell activation and cytokine production. IL-10 Deficiency leads to severe inflammatory bowel disease in humans and mice; the mechanism of inflammation suppression by IL-10 is not fully understood.
Groux & Cottrez 2003 J Autoimmun 20: 281-285
Saraiva & O’Garra 2010 Nat Rev Immunol 10: 170-181
Glocker et al. 2011 Ann NY Acad Sci 1246: 102-107
Li et al. 2014 Mucosal Immunol 7: 869-878
Zhu et al. 2017 Gastroenterology Res 10: 65-69

Interleukin-10 (IL-10) signaling regulates [sphingolipid metabolism](brain://aIirqsCxYkerZcB-Zq1HEQ/MetabolicRegu…