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Depression is a leading cause of disability worldwide and can lead to suicide, the second leading cause of death in people between the ages of 15 and 29.
Global surveys show that 5% of the world population (approx. 300 million people) suffer from mood disorders
Monoamine insufficiency is suggested to be associated with depressive features such as sadness, anhedonia, insomnia, and cognitive dysfunction, but the mechanisms that cause it are unclear
Depression in adolescents is increasing at a greater rate than in adults. Change in appetite, loss of energy, and insomnia may be more apparent than mood changes. Pharmacologic treatment and psych…