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Conjugated Primary Bile Acids

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Conjugated primary bile acids, mainly glycocholic acid (GCA) and Taurocholate (TCA), Taurocholic Acid, are kept in the gallbladder. They remain there until a meal is consumed, which then prompts their release into the duodenum.
Rimal et al. 2024 Nature 626: 859-863

Bile salt hydrolases are enzymes typically present in bacteria residing in the small intestine and colon. It functions by hydrolyzing the amide linkage of [conjugated bile acids](bra…