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Eomesodermin (Eomes)
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Contents
Eomes was a direct target of miR-107
Rapamycin inhibits mTOR signaling, which can promote the generation of memory T cells.
Eomes is highly expressed in memory T cells
The mTOR signaling pathways have been demonstrated to regulate the expression of Eomes in [CD8+ T cells](brain://s-pKF05-6kiTAg3gOHqyZQ/C…
References (Sources)
- Cutting edge: the transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche
- Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
- Metformin Enhances the Antitumor Activity of CD8+ T Lymphocytes via the AMPK-miR-107-Eomes-PD-1 Pathway
- Modulation of mTOR signalling triggers the formation of stem cell-like memory T cells
- The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin