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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Eomesodermin (Eomes)

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Eomes was a direct target of miR-107
Zhang et al. 2020ab J Immunol. 204(9): 2575-2588

Rapamycin inhibits mTOR signaling, which can promote the generation of memory T cells.
Scholz et al. 2016 EBioMedicine 4: 50-61

Eomes is highly expressed in memory T cells
Banerjee et al. 2010 J Immunol 185: 4988-4992

The mTOR signaling pathways have been demonstrated to regulate the expression of Eomes in [CD8+ T cells](brain://s-pKF05-6kiTAg3gOHqyZQ/C…

Cutting edge: the transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche
Banerjee et al. 2010 J Immunol 185: 4988-4992
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
Intlekoferet al. 2005 Nat Immunol 6: 1236-1244
Review
Metformin Enhances the Antitumor Activity of CD8+ T Lymphocytes via the AMPK-miR-107-Eomes-PD-1 Pathway
Zhang et al. 2020ab J Immunol. 204(9): 2575-2588
Modulation of mTOR signalling triggers the formation of stem cell-like memory T cells
Scholz et al. 2016 EBioMedicine 4: 50-61
The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin
Rao et al. 2010 Immunity 32: 67-78

12/16/2025