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The enzyme complex AppBCX promotes the outgrowth of E. coli in murine models of gut inflammation
AppBCX respiration requires reactive oxygen species produced by epithelial NADPH oxidase 1 (NOX1)
Hydrogen peroxide, detoxified to oxygen, supports AppBCX respiration in vitro
Biochemical analyses of the isolated AppBCX enzyme complex suggest it reduces oxygen while oxidizing quinol and thus functions as a terminal oxidase, akin to CydABX
Sturr et al. 1996 J. Bacteriol. 178: …