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Cholesterol dehydrogenases, also known as hydroxysteroid dehydrogenases (HSDHs), are enzymes that play a crucial role in the metabolism of steroid hormones, including bile acids and glucocorticoids. These enzymes are found in both host tissues and gut microbiota, and they catalyze the reversible conversion of steroid hydroxyl groups to keto groups.
Doden & Ridlon 2021 Microorganisms 9(3):469
see also:
Catabolism & Cholesterol
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