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The Alfa-Bug Hypothesis suggested that oncogenic bacteria such as Enterotoxigenic Bacteroides fragilis (ETBF) induce the development of CRC through direct interactions with colonic epithelial cells and alterations of microbiota composition at the colorectal site
Enterotoxigenic Bacteroides fragilis as oncogenic bacteria belongs to pathogenic bacteria. The presence of enterotoxigenic Bacteroides fragilis has been demonstrated in human biopsies of various typ…