meRfi®-GM
Interleukin-15 (IL-15)
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Interleukin-15 (IL-15) = T-cell growth factor, produced by dendritic cells, macophages, stromal cells, acts on CD8 und CD4 cells
Interleukin-15 (IL-15) shares many functions with IL-2, including stimulation of ADCC…
References (Sources)
- Interactions between the tumor suppressor p53 and immune responsesReview
- Progressive loss of RORγt expression confers distinct functional fates to natural killer cell receptor-expressing RORγt+ innate lymphocytes
- Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies