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CD223 (Lymphocyte Activation Gene 3 Protein) (LAG-3)

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Aliases: LAG3, CD223, lymphocyte activating 3

Lymphocyte activation gene-3 (LAG-3) is a member of the immunoglobulin superfamily. Engagement of LAG-3 by its ligands to trigger downstream signaling can inhibit immune responses and regulate the pathogenesis of many diseases, including cancer and inflammatory diseases.
Tian et al. 2022 Expert Review of Anticancer Therapy 22(3): 289-296