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The acute phase response (APR) is a rapid, early-phase systemic reaction to disturbances such as infection, inflammation, or trauma.
It is characterized by a series of events that include the release of acute-phase proteins (APPs) into the bloodstream, which are produced mainly by the liver in response to cytokines like interleukin-6 (IL-6), interleukin-1 (IL-1), [tumor necrosis factor-alpha (TNF-alfa)](brain://roB44vrlq…