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Clostridioides difficile infection (CDI) (recurrent) is caused by persistent disruptions of the gut microbiome, typically characterized by reduced proportions of the bacterial phyla Bacillota, Bacteroidota, and Actinomycetota, and an increased proportion of the phylum Pseudomonadota.
Okhuysen et al. 2024 Clin Infect Dis 78: 1462-72
The diversity of the fecal microbiome is reduced in cases of recurrent Clostridium diff…