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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Amuc_1100

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Amuc-1100 binds to Toll-like receptor 2 (TLR2)
Cani et al. 2022 Nat Rev Gastroenterol Hepatol 19(10): 625-637

In the context of cancer or inflammatory bowel diseases, A. muciniphila and Amuc_1100 regulate the differentiation of immune cells in mice
Cani et al. 2022 Nat Rev Gastroenterol Hepatol 19(10): 625-637

Both A. muciniphila and Amuc_1100 increase the differentiation of T reg cells in the colon
Cani et al…

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8 +T cells in mice
Wang et al. 2020ai Gut 69: 1988-1997
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
Plovier et al. 2017 Nat. Med. 23: 107-113
Akkermansia muciniphila: key player in metabolic and gastrointestinal disorders
Macchione et al. 2019 Eur. Rev. Med. Pharmacol. Sci. 23: 8075-8083
Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
Cani et al. 2022 Nat Rev Gastroenterol Hepatol 19(10): 625-637
Review
The outer membrane protein Amuc_1100 of Akkermansia muciniphila promotes intestinal 5-HT biosynthesis and extracellular availability through TLR2 signalling
Wang et al. 2021u Food Funct. 12: 3597-3610

5/29/2026