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The generation of Interleukin-4 (IL-4) by Group 2 ILCs (ILC2) is affected by factors like diet and the presence of particular transcriptional elements.
Group 2 ILCs (ILC2) -derived Interleukin-4 (IL-4) is crucial in encouraging Th2 differentiation during helminthic infections (e.g., Heligmosomoides polygyrus infection) and allergies.
Pelly et al. 2016 Mucosal Immunol 9(6): 1…