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Disruption of epithelial hypoxia and a subsequent increase in the amount of oxygen emanating into the colonic lumen can cause the bloom of facultative anaerobic bacteria, a group associated with intestinal dysbiosis and inflammatory diseases (IM)
Byndloss 2020 Science 369: 153A
Hypoxia promotes drug resistance and induces the expression of hypoxia-inducible factor (HIF)‑1alpha
Hypoxia induces shedding of NK cell-activating ligands (MICA) from the cell surface.
Hypoxia upregulates VISTA expression in [TME](brain://iNKwG…