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Autism Spectrum Disorders (ASD)
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Autism Spectrum Disorders (ASD), characterized by social difficulties and restricted and repetitive behaviors and interests, affects 1-2% of the population.
Autism spectrum disorders (ASD) are complex neurobiological disorders with pervasive neurodevelopmental disabilities that impair social interactions and communication and lead to restricted, repetitive, and stereotyped behavior patterns, interests, and activities
Kang et al. 2017a Microbiome 5(1): 10
Notably, many individuals with ASD experience concurrent gastrointestinal (GI) symptoms, suggesting a connection between the gut and the brain.
ASD generally occurs early in childhood a…
References (Sources)
- Altered brain-gut axis in autism: comorbidity or causative mechanisms?
- Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis
- Gastrointestinal symptoms in autism spectrum disorder: a meta-analysisMeta-Analysis
- Infant microbes and metabolites point to childhood neurodevelopmental disorders
- Nitric oxide pathway as a plausible therapeutic target in autism spectrum disorders
- Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder
- Proteomics and Metabolomics Approaches towards a Functional Insight onto AUTISM Spectrum Disorders: Phenotype Stratification and Biomarker DiscoveryReview