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Infection Diseases / Infections / Bacterial Infection
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Contents
The prevalence of death from infection in unvaccinated humans is generally driven by age.
Bacterial infection occurs through Toll pathway and Immune deficiency (IMD) pathway
There is enormous individual clinical variation in the course of any infection
No more than a dozen known microbes can kill more than 10% of infected individuals, even without medical prevention and treatment. Fewer than 100 microbes can kill more than 1% of infected individuals. Most of the remaining 3,000 known pathogens are less virulent and cause life-threatening disease in <1% of infected individuals. The obse…
References (Sources)
- 1918 Influenza: the mother of all pandemics
- A Case for Phosphoinositide 3-Kinase–(PI3K) Targeted Therapy for Infectious Disease
- Epidemiology of sexually transmitted diseases: the global picture
- Human determinants of age-dependent patterns of death from infection
- Infections at the maternal-fetal interface: an overview of pathogenesis and defence
- Infectious and lifestyle modifiers of immunity and host resilience
- Lethal Infectious Diseases as Inborn Errors of Immunity: Toward a Synthesis of the Germ and Genetic Theories