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Whole genome metagenomics sequencing of stool samples from patients with Inflammatory bowel disease (IBD) and a retrospective analysis of electronic medical records over 10 years after sample collection stratified by patients who required and did not require therapy intensification revealed:
The gut microbiota (12 microbial species (e.g., Roseburia hominis and Dialister invisus and 16 functional pathways (e.g., biosynthesis of L-citrulline and L-threonine) are potential biomarkers for treatment intensification …