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Vibrio cholerae

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Vibrio cholerae is a Gram-negative, comma-shaped bacterium. It is typically found in brackish water and estuaries, often associated with plankton. There are over 200 serogroups of Vibrio cholerae, but only two serogroups, O1 and O139, are known to cause cholera outbreaks.

Type VI secretion system-mediated cell death in Vibrio cholerae colonies occurs in two space- and time-differentiated phases that cause death along the colony rim and interior, respectively. Cell death at the colony rim is a consequence of kin- killing and is proposed to drive genetic diversity in nature and during disease
Mashruwala et al. 2022 Cell 185: 3966-3979

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