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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Tryptophan (TRP)

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From tryptophan, Serotonin (5-HT), melatonin, and NAD are formed. The availability of Tryptophan (TRP) is determined by dietary intake in relation to its use for protein synthesis and metabolic processes.
Liu et al. 2025 Trends in Cancer 11(7): 629-641

Tryptophan (Trp) is an essential amino acid that can only be obtained through diet
Mohseni et al. 2023 Cancer Res 83(7_Suppl): Abstract nr 644

Tryptophan (Trp) is an essential amino acid, which can be naturally provided by dietary proteins such as poultry, milk, tuna, ﬁsh, cheese, [br…

References (Sources)

Gut microbial metabolites of aromatic amino acids as signals in host–microbe interplay
Liu et al. 2020 Trends Endocrinol. Metab. 31: 818-834
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
Agus et al. 2018 Cell Host Microbe 23: 716-724
Review
Malnutrition and Dietary Habits Alter the Immune System Which May Consequently Inﬂuence SARS-CoV-2 Virulence: A Review
Foolchand et al. 2022 Int. J. Mol. Sci. 23: 2654
Review
Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions
Zhang & Davies 2016 Genome Med. 8(1): 46
Review
New insights into tryptophan metabolism in cancer
Liu et al. 2025 Trends in Cancer 11(7): 629-641
Review
Plasma concentrations and intakes of amino acids in male meat-eaters, ﬁsh-eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort
Schmidt et al. 2016 Eur J Clin Nutr 70: 306-312
Tryptophan biochemistry: structural, nutritional, metabolic, and medical aspects in humans
Palego et al. 2016 J Amino Acids 2016: 8952520
Review

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12/16/2025

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Tryptophan - Wikipedia