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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

SAM domain and HD domain-containing protein 1 (SAMHD1)

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In humans, SAMHD1 hydrolyzes deoxynucleotides triphosphates during HIV-1 infection.
Goldstone et al. 2011 Nature 480: 379-382

SAMHD1 depletes the pool of Deoxynucleoside triphosphate (dNTP) / Nucleotide.
Goldstone et al. 2011 Nature 480: 379-382
Tal et al. 2022 Nat. Microbiol. 7: 1200-1209
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Bacteria deplete deoxynucleotides to defend against bacteriophage infection
Tal et al. 2022 Nat. Microbiol. 7: 1200-1209
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
Goldstone et al. 2011 Nature 480: 379-382

5/29/2026