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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Mucins & O-Glycans / O-Linked Glycosylation

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Aberrant glycosylation creates novel cancer-specific glycoantigens that can interact with cells of the immune system via carbohydrate-binding lectins
Beatson et al. 2015

Mucin-like O-glycan structures are characteristic of numerous types of human tumor cells
Zenina et al., 2008

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References (Sources)

Carbohydrate-active enzymes from Akkermansia muciniphila break down mucin O-glycans to completion
Bakshani et al. 2025 Nat Microbiol 10(2): 585-598
Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions
Brockhausen 2006
Protein glycosylation in cancer
Stowell et al. 2015 Annu Rev Pathol 10: 473-510
Review
The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
Beatson et al. 2015
The Study of Immunological Component in AntiTumor Effect of Trypanosoma Cruzi
Zenina et al., 2008

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12/16/2025

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Mucins & O-Glycans / O-Linked Glycosylation

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