meRfi®-GM
adenomatous polyposis coli (apc) gene
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Contents
MyD88-dependent signaling therefore contributes substantially to the severe mortality and morbidity caused by inactivation of APC (multiple intestinal neoplasia allele of the adenomatous polyposis coli gene)
Rakoff–Nahoum & Medzhitov 2007 Science 317: 124–7…
References (Sources)
- Intestinal neoplasia in the Apc Min mouse: independence from the microbial and natural killer (beige locus) status
- Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC gene mutation
- Regulation of spontaneous intestinal tumorigenesis through the adaptor protein myd88