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White Adipose Tissue (WAT) refers to a type of adipose tissue that mainly functions to store energy as triglycerides. It is distinguished by its white or yellowish color, which results from its high lipid content.
White adipose tissue plays a well-known role in energy balance and homeostasis by storing and mobilizing lipids. The immune system has emerged as a central regulator of adipose tissue function and dysfunction, with the balance between anti-inflammatory and inflammatory immune cells playing a key role in influencing metabolic health. In the lean state, adipose tissue resident immune cells are mostly anti-inflammatory and promote tissue homeostasis, while during obesity the balance shifts towards a proinfl…