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C1q is co-expressed in healthy and tumor macrophages with human leukocyte antigen DR (HLA-DR), apolipoprotein E (APOE) and mannose receptor C-type 1 (MRC1) (MRC1) (CD206).
Complement C1q pops up as a marker of a tolerogenic and immunosupressive macrophage populations in both healthy and tumor tissues.
see also:
C1q macrophages