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Pan-Cyclin-dependent kinase (CDK) inhibitors are compounds that broadly inhibit multiple Cyclin-dependent kinases (CDKs), which are key regulators of cell cycle progression and transcription. Unlike selective cyclin-dependent kinase (CDK) inhibitors, Pan-Cyclin-dependent kinase (CDK) inhibitors block the activity of several CDK family members at once, potentially halting cell division and growth in cancer cells, but often with higher toxicity due to their broad action
Early Pan-Cyclin-depende…