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The genus Fusobacterium comprises Gram-negative rod-shaped bacteria. These bacteria primarily ferment carbohydrates and amino acids, producing acetate, butyrate, and lactate as metabolic by-products.
Historically, Fusobacterium species were classified based on their morphology and their ability to ferment amino acids and glucose into butyrate.
In the context of tumor development, adenomas can become colonized by 'passenger' bacteria such as Fusobacterium species, which facilitate tumor progression.
Tjalsma et al. 2012 Nature Reviews Microbiology 10: 575-582
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