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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Surface Layer Proteins (SLPs)

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The function of Surface Layer Proteins (SLPs) in bacterial adhesion and gut barrier protection can be attributed to Surface Layer Proteins (SLPs)’ competition with pathogens such as enterohemorrhagic E. coli (EHEC), enteroinvasive E. coli (EIEC) and enteropathogenic E. coli (EPEC) for adhesion sites on the intestinal cell surface
Liu et al. 2020a

Purified Surface Layer Proteins (SLPs) from L. plantarum exert a protective effect on [Caco-2 cells](brain:…

Bacterial S-layers
Sleytr & Beveridge 1999 Trends Microbiol. 7: 253-60
Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens
Lebeer et al. 2010 Nat Rev Microbiol 8: 171-184
Review
Lactobacillus plantarum surface layer adhesive protein protects intestinal epithelial cells against tight junction injury induced by enteropathogenic Escherichia coli
Liu et al. 2011e Mol Biol Rep. 38: 3471-80
Not just for eukarya anymore: protein glycosylation in bacteria and archaea
Abu-Qarn et al. 2008 Curr Opin Struct Biol. 18: 544-50
Nutrient transport suggests an evolutionary basis for charged archaeal surface layer proteins
Li et al. 2018e ISME J. 12: 2389-402
Surface components and metabolites of probiotics for regulation of intestinal epithelial barrier
Liu et al. 2020a
Review
The archaeal cell envelope
Albers & Meyer 2011 Nat Rev Microbiol. 9: 414-26

2/26/2026