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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Bacterial Metabolites / Microbial Metabolites & Cardio-metabolic diseases (CMD)

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Contents

Trimethylamine (TMA) (Wang et al. 2015b; Dambrova et al. 2016 Exp Clin Endocrinol Diabetes 124(04): 251-256; Randrianarisoa et al. 2016 Scientific Reports. 6(1): 1-9; Zhu et al. 2016 Cell 165: 111-124; Schugar et al. 2017 Cell Reports 19 (12): 2451-2461), bile acids (Hylemon et al. 2009 J Lipid Res. 50(8):1509-1520; Wahlström et al. 2016 Cell Metab. 24: 41-50; Joyce & Gahan 2017 Dig Dis. 35(3): 169-77; Vítek 2017 Annals Hepatol. 16(1): 43-52) are examples of metabolic products that have been negatively associated with CMD
Nogal et al. 2021 Gut Microbes 13(1): e1897212

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References (Sources)

Bile acids in the treatment of cardiometabolic diseases
Vítek 2017 Annals Hepatol. 16(1): 43-52
Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity
Menni et al. 2019a Gut Microbes 16(10): 688-695
Diabetes is associated with higher trimethylamine N-oxide plasma levels
Dambrova et al. 2016 Exp Clin Endocrinol Diabetes 124(04): 251-256
Disease-associated changes in bile acid profiles and links to altered gut microbiota
Joyce & Gahan 2017 Dig Dis. 35(3): 169-77
Review
Microbial modulation of cardiovascular disease
Brown & Hazen 2018 Nat. Rev. Microbiol. 16: 171-181
Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis
Wang et al. 2015b Cell 163(7): 1585-1595
The TMAO-producing enzyme flavin-containing monooxygenase 3 regulates obesity and the beiging of white adipose tissue
Schugar et al. 2017 Cell Reports 19 (12): 2451-2461

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5/29/2026

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