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Dysregulation of various cellular processes in the gastric epithelium and in different cells of the microenvironment is a hallmark of H. pylori infection
Myeloid-specific deletion of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine synthesis, promoted M1 immune response and therefore significantly enhanced gastritis during Helicobacter pylori infection, but alleviated DSS-induced colitis
Helicobacter pylori infection upregulates NF-kB to induce inflammation in the stomach (Ya…