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Clostridium Cluster IV
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Clostridium cluster IV is also known as the Clostridium leptum group within the Firmicutes phylum. It comprises at least 8 bacterial species, including 4 in the Clostridium genus and 4 outside it
This cluster is significant due to its role in the human microbiome, where it, along with Clostridium Cluster XIVa, represents a major component of the gut's bacterial population, contributing to 10%–40% of the total bacteria present
The bacteria within Clostridium Cluster IV are involved in various beneficial processes, including the production of short-chain fatty acids like butyrate, which is essential for …
References (Sources)
- Abnormal microbiota composition in the ileocolonic mucosa of Crohn’s disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis
- Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
- Induction of colonic regulatory T cells by indigenous Clostridium species
- Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases.
- Probiotic Potential of Clostridium spp.-Advantages and Doubts
- Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach
- The gut microbiome in health and in disease