meRfi®-GM
MyD88/TRAF6 pathway
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Contents
The activation of the MyD88/TRAF6 pathway leads to the activation of various downstream signaling molecules, including NFKB. This results in the production of pro-inflammatory cytokines and the initiation of innate immune responses.
Activation can occur via Interleukin-1 (IL-1) receptors (IL-1R) as well as through Toll-Like Receptors (TLRs) (TLR1 / TLR2 Heterodimer (TLR1/TLR2), [TLR2 / TLR6 Heterodimer (TLR2/TLR6)](brain://7lNWcmG0IECq7WbDBHOyOg/Tlr2Tlr6HeterodimerTlr2tl…