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Myeloid Differentiation Primary Response 88 (MYD88) is the most common and universal adaptor protein for all Toll-Like Receptors (TLRs) except for Toll-like receptor 3 (TLR-3) connecting signals from outside the cell to the proteins that relay signals inside the cell.
By attaching to their ligands and experiencing conformational changes, the recruit of the MyD88 adaptive molecule and interaction with the intracellular domain of Toll-Like Receptors (TLRs) follow.
Chen e…