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Lysine-epsilon-acetylation is a type of post-translational modification that changes the biochemical properties of numerous proteins. This reaction is facilitated by enzymes known as histone/protein acetyltransferases (HATs) and can be reversed by histone/protein deacetylases (HDACs). Therefore, HATs and HDACs play crucial roles in regulating the functions of Regulatory T cells (Tregs). In particular, enzymes like [Histone deacetylase 6 (HDAC6)](brain://VNLyqtrJzkmD62FqfkKD1Q/HistoneDeacetyla…