NFKB Activation

NFKB activity was associated with the production of the pro-inflammatory cytokines IL-1, IL-6 and TNF-alfa
Neurath et al. 1996 Nat Med 2(9): 998-1004

Nuclear translocation and activation of NFKB and binding of DNA occurs with the participation of five protein dimers: p50, p52, p65 (RelA), RelB, and c-Rel
Lawrence 2009 Cold Spring Harb Perspect Biol 1(6): a001651
Oeckinghaus et al. 2011 Nat Immunol 12(8): 695-708
Zhang et al. 2017a Cell 168(1-2): 37-57

see also:
Diseases / Disorders & NF kappa B (NFKB) / NFKB Family