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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

Heart Failure / Congestive Heart Failure (CHF)

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Heart failure (HF), a complex clinical syndrome, is characterized by the heart's inability to pump sufficient blood to meet the body's needs.

The prevalence of heart failure in adults is 1 to 2% and in over 70-year-old >10%.
Mosterd & Hoes 2007 Heart 93(9): 1137-1146
McMurray et al. 2012 European Heart Journal 33(14): 1787-1847

Heart failure is a difficult clinical syndrome with abnormal changes in the structure and function of the heart. Heart failure leads to ventricular systolic and or diastolic dysfunction Ponikowski et al. 2016 European Heart Journal 37(27): 2129-2200

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References (Sources)

2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure
Ponikowski et al. 2016 European Heart Journal 37(27): 2129-2200
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection
Mills et al. 2021
Catheter Ablation for Atrial Fibrillation with Heart Failure
Marrouche et al. 2018 NEJM 378: 417-427
CD36 as a target for metabolic modulation therapy in cardiac disease
Glatz et al. 2021 Expert Opin.Ther.Targ. 25: 393-400
Review
Clinical epidemiology of heart failure
Mosterd & Hoes 2007 Heart 93(9): 1137-1146
Review
ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European society of cardiology. Developed in collaboration with the heart failure association (HFA) of the ESC
McMurray et al. 2012 European Heart Journal 33(14): 1787-1847
STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3
Li et al. 2019m Redox Biol. 24: 101215

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